Abstract:In the paper, combined enzymes were used for the hydrolysis of Antarctic krill Euphausia superba to obtain polypeptides, and the polypeptides contents and molecular weight distribution were determined by biuret method and liquid chromatography respectively. The antimicrobial activity of peptides and different molecular-weight fractions of polypeptides to six strains including Staphylococcus aureus, Bacillus subtilis, Micrococcus tetragenus, Escherichia coli, Saccharomyces cerevisiae, and Vibrio parahaemolyticus was carried out by the filter paper method. The results showed that polypeptides contents of the hydrolysate was 81.44% and the range of peptides molecular weight was 254~10 000. The polypeptides from Antarctic krill presented obvious antibacterial activity to S. aureus, and fraction Ⅲ（Mr＜3.0×103） showed the strongest antimicrobial activity.
