Elimination of ciprofloxacinum in Chinese mitten crab Eriocheir sinensis

Abstract:

The elimination of ciprofloxacinum residue in Chinese mitten crab Eriocheir sinensis under different culture conditions was studied by using Ultra Performance Liquid Chromatography coupled with Mass Spectrometry (UPLC-MS). The results showed that the elimination was so slow that even at 35-day after administration, the levels of ciprofloxacinum residue in all groups of E. sinensis were higher than the instrument detection limit. The elimination rate was faster at 28℃ than at 22℃, in the fifth stage larvae than in the button crabs, and in outdoor open water than the indoor environment.