Abstract:Fenneropenaeus chinensis were fed with norfloxacin (NFLX) at doses of 15mg/kg (low dose group), 30mg/kg (medium dose group), and 60mg/kg (high dose group) for 7 days, respectively. The activities of some non-specific immune response enzymes including superoxide dismutase (SOD), catalase (CAT), lysozyme (LSZ), phosphatase (ACP), and alkaline phosphatase (AKP) in the muscle and gill tissues of the fed shrimps were determined. For the low dose group, the SOD activities in the muscle were significantly lower than that of the control group (P<0.05), while the SOD activities in the gill increased. The activities of CAT and LSZ in the muscle and gill were significantly higher than those of the control group (P<0.05), and the activities of ACP and AKP were inhibited. For the medium dose group, CAT activity in shrimps was significantly higher than that in the control group. The LSZ, and SOD activities in the muscles were first inhibited, and then increased. The SOD, LSZ and CAT activities in the muscle and gill were activated by 60mg/kg NFLX, while the AKP and ACP activities showed no significant difference between the experimental groups and the control (P<0.05).
