Abstract:The inhibitory effects of 18 Chinese herbs on Vibrio anguillarium, V. prarhaemalyticus, V. aestuarianus and V. cholerae were tested by disc diffusion method (punch method). The results showed that 7 Chinese herbs including Galla chinensis, Caesalpinia sappan, Herba euphorbiae, pomegranate bark, Radix scutellariae, Polygonum cuspidatum and Fructus Crataegi can effectively inhibit the growth of 4 pathogenic Vibrio sp., and the other 11 Chinese herbs showed less inhibition. At the same time, the minimal inhibitory concentration and the minimum bactericidal concentration of the 7 Chinese herbs which had significant inhibitory effects to Vibrio sp. were tested by the tube dilution.The results showed that Caesalpinia sappan, Galla chinensis, Herba euphorbiae and Pomegranate bark had significant inhibitory and bactericidal effects, and the minimal inhibitory concentrations of Caesalpinia sappan, Galla chinensis, Herba euphorbiae and Pomegranate bark for 4 pathogenic Vibrio sp. were among 0.78~6.25 mg/ml, the minimal bactericidal concentrations were 3.12~12.5 mg/ml.
