Preliminary study on isolation, purification and characteristics of a toxin from jellyfish

Abstract:

A toxin, named RE 5 6，was isolated, purified and characterized from the tentacles of Rhopilema esculentum by Sephadex G 10 gel filtration and SP Sephadex C 25. The molecular weight was 662 kD. RE 5 6 showed hemolytic activity to chicken blood; its analgesic effect to mice was significant and intensified with concentration increasing; it showed medium or low level stimulation the skin and eyes of mice; it also inhibited the growth of Escherichia coli and Candida albicans. No serine protease inhibiting activity was revealed by the examination. KEY WORDSJellyfish Rhopilema esculentumToxinHaemolytic activity